Member of Hamas political bureau, Mousa Abu Marzouq, a father of six children, was born on February 9, 1951 in Rafah City in the southern Gaza Strip.

His family was forcibly dispossessed of their home in Yibna town south of the occupied Palestinian city of Askalan during the 1948 ethnic cleansing of the Palestinian people.

Abu Marzouq received his elementary education in the Gaza Strip. But in protest against the educational system controlled by the Israeli occupation following its occupation to the Gaza Strip in 1967, he chose to study high school from home.

In 1975, he graduated with a BSc in mechanical engineering majoring in production engineering from Helwan University in Egypt.

Abu Marzouq obtained his master's degree in construction management in 1984 in the United States of America. Eight years later in 1992, he finished his Ph.D. in mechanical engineering.

From 1976 to 1981, he worked as the director of an aluminum factory in the United Arab Emirates and as an engineer in the Abu Dhabi National Oil Company (ADNOC).

Abu Marzouq helped establish the first Muslim center in Fort Collins in northern Colorado and several institutions, centers, schools, and organizations advocating for the Palestinian cause in the US.

One of the founders of the Islamic University of Gaza, Abu Marzouq was appointed as a member of its supervisory board. He also was a member of the Arab National Congress and became a member of the first administrative board of the National Islamic Conference.

Appointed head of the preparatory committee to establish the Al-Quds International Institution, Abu Marzouq headed its board of directors in its first session and is still a member of it.

Abu Marzouq, along with fellows, established the first bureau of the Palestinian Muslim Brotherhood in the UAE and helped found the movement's unified coordination office.

After the Palestinian and Jordanian branches of the Muslim Brotherhood were unified, Abu Marzouq was elected as head of the alliance's UAE bureau and a member of its General Shura (consultative) Council and Executive Office. In 1988, Abu Marzouq was elected as head of the Islamic Action in the US, where he helped establish a number of Muslim centers and societies.

One of the founders of the Palestinian Islamic Resistance Movement Hamas, Abu Marzouq restructured the Palestinian movement after Israeli occupation forces detained its senior leaders and officials and most of its members in 1989.

Three years later, Abu Marzouq was elected as the first chairman of the Hamas political bureau. In mid-1995, the Jordanian authorities deported him from Amman after closing his office in the Jordanian capital. He headed the movement's office at the time.

On 5 July 1995, the US authorities detained him at an airport in New York City and held him for 22 months in solitary confinement without charge before extraditing him to Jordan in May 1997.

After his release from the US custody, Abu Marzouq served as the deputy chief of the Hamas political bureau until 2017. Two years later, the Jordanian authorities banished him for the second time after issuing arrest warrants for Hamas officials in the country. After leaving Jordan, Abu Marzouq resided in Syria, then moved to Egypt before heading to Qatar.

Since 2009, Abu Marzouq led the Hamas delegation in the Cairo talks to achieve Palestinian reconciliation after the formation of the Palestinian National Consensus Government in 2014.